Synthesis, Characterization, and Antitumor Activity of Four Novel Sulphonamide compounds
نویسندگان
چکیده
Abstract: A selected series of substituted sulphonamides were synthesized. These compounds were tested for potential antitumor activity against three of human tumor cell lines, Liver carcinoma cell line [HEPG2], Brain tumor cell line [U251] and Colon carcinoma cell line [HCT116]. Cytotoxic activity was assessed by SRB assay. The structures of the resulting compounds have been investigated by elemental microanalysis, H NMR and FT-IR analyses. These results indicate that the sulphonamide 1
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